D-CAT

Clinical application tool to support dengue management in low and middle income countries.

Role: Postdoctoral researcher bridging the gap between clinicians and software developers

Dengue epidemics can rapidly increase demand in healthcare services across many endemic settings. However, there remains a lack of tools which can rapidly inform patient management and can be used at the point of care. Digital clinical decision-support systems (CDSS) allow for efficient organisation of care as well as improve the quality of patient management. It is important that these tools are designed for the end-user and with the healthcare setting in mind to increase adoption and usability.

We adopted a ground-up human-centred design approach to design a digital CDSS system for dengue management in Vietnam (D-CAT). A multidisciplinary team of data scientists, clinicians and social scientists were involved in a series of activities designed to map clinical processes, essential tasks and decision-making priorities which were crucial in the management of dengue at our hospital setting [1]. The desired features for the CDSS identified were: i) patient organisation, ii) availability of guidelines and calculators with easy access, iii) display of results and iv) inference models for dengue diagnosis on admission [2] and further risk-stratification for hospitalised patients based on possible complications [3]. A web-based reactive framework suitable for display on computers and tablets was produced. Priority was placed on usability and modularity so that the system can be re-purposed.

Dengue Clinical Application Tool (D-CAT) is a bespoke and rapidly scalable CDSS produced following clinical pathways, clinician’s needs, and usability in mind. Further work will focus on prospective evaluation and iterative improvement of the CDSS including (i) end-user testing and (ii) prospective model performance. If successful, the CDSS will be implemented and deployed to evaluate its clinical utility.


Publications

  1. Mapping patient pathways and understanding clinical decision-making in dengue management to inform the development of digital health tools
    Quang Huy Nguyen, Damien K Ming, An Phuoc Luu, and 8 more authors
    BMC Medical Informatics and Decision Making Feb 2023
  1. A human-centred design approach towards development of a digital clinical decision-support system for management of hospitalised patients with dengue
    Bernard Hernandez, Damien K Ming, Chanh Ho Quang, and 15 more authors
    In International Conference on Infectious Diseases Nov 2022
  1. The Diagnosis of Dengue in Patients Presenting With Acute Febrile Illness Using Supervised Machine Learning and Impact of Seasonality
    Damien K Ming, Nguyen M Tuan, Bernard Hernandez, and 8 more authors
    Frontiers in Digital Health Mar 2022
  1. Applied machine learning for the risk-stratification and clinical decision support of hospitalised patients with dengue in Vietnam
    Damien K Ming, Bernard Hernandez, Sorawat Sangkaew, and 8 more authors
    PLOS Digital Health Jan 2022